OntoChem News

 

January 31, 2012

PhytoBase® -  Ontochem's comprehensive dynamic plant database

Ontochem GmbH is using its text analysis and knowledge mining technologies to retrieve information about plants, natural products that occur in these plants, their uses and biological activities, as well as molecular pathways including proteins and genes. From this extracted information a comprehensive and dynamic database is created that contains qualified relationships between plants, compounds, proteins, genes, pathways and biological activities and uses.

 

October 12, 2011

Ontochem and Priaxon Join Forces to Increase Stress Tolerance of Crops

Ontochem GmbH and Priaxon AG, Munich, Germany today announced the entry into a collaboration and commercialization agreement to obtain new superior inhibitors of the plant PARP, poly(ADP-ribose)polymerase enzyme. The goal of this collaboration is to increase the intrinsic stress tolerance of agricultural crops and accordingly minimizing growth losses by abiotic stress. Multinational companies are trying to solve the problem by genetically modified crops, requiring extensive development time and approval procedures per plant species. In contrast, the PARP inhibitors of this cooperation shall be applicable to all crop species without causing any health problems to other species. Genetic engineering will not be an issue for the development.

Approximately 40% of all crop losses are induced by abiotic stress, whereas only 20% are caused by insects or weeds. Typical abiotic stress factors are drought, UV radiation and soil loading by salts. The plant enzyme PARP is only being activated under stress conditions. When activated, metabolic PARP processes consume a lot of energy resources of the plant, which are than missing for the normal growth of the plant.

In this Biotech-Biotech cooperation Ontochem will explore and optimize the biological efficacy of novel inhibitors on enzymes and plants. In parallel, the effects on insects and other animals are examined and excluded. Priaxon takes over the planning and syntheses of new potential inhibitors.

"We are delighted to be working with Ontochem whom we recognize as leaders in the biology of plant PARP," said Dr. Jürgen Kolb, Chief Executive Officer of Priaxon.

"Priaxon has developed an efficient toolbox for the design and synthesis of biologically active compounds - we are confident to identify useful products in a rather short time period in this collaboration", said Lutz Weber, Chief Executive Officer of Ontochem.

 

August 31, 2010

OntoChem has released its first version of OCMiner

OntoChem has implemented its OCMiner technology as an ontology search engine for biomedical scientific documents in the life science industry. The first OCMiner server was installed successfully at the site of its its first customer, a large life science company.

 

June 10, 2010

OntoChem expands its service customer basis

OntoChem is using its biology screening capabilities in a long term service contract with the German Biotech Priaxon AG.

 

June 8, 2010

OntoChem expands its service customer basis

OntoChem is using its drug design and bioinformatics capabilities in a long term service contract with the Italian Biotech Adriacell S.p.a.

 

April 27-29, 2009

OntoChem presents its OCMiner knowledge extraction technology at the BioITWorld2009

Annotating and searching chemical compounds and concepts together with life science ontologies such as diseases, anatomy, taxonomies and biological targets in text documents, patents and databases is straightforward with OCMiner

 

April 27-29, 2009

Omixon and OntoChem present their joint MolFinder solution at the BioITWorld2009

The custom chemistry space of synthetically feasible compounds of chemical suppliers is orders of magnitudes larger than what they offer off the shelf - made accessible via MolFinder

 

October 1, 2008

OntoChem starts own biology laboratory to validate knowledge generated by its proprietary data mining system

 

June 19, 2008

OntoChem gewinnt 1. Preis beim Wettbewerb "IQ Innovationspreis Halle"

 

January 1, 2008

OntoChem moves into new offices at Technologie- und Gründerzentrum III in Halle

 

July 1, 2007

Sparkassenbeteiligungsgesellschaft Sachsen-Anhalt investiert in OntoChem GmbH

 

June 10, 2007

OntoChem is partner of the hungarian MMP consortium

 

December 13, 2006

OntoChem was a winner of the Microsoft "IT-Founders" price

 

September 21, 2006

OntoChem was a winner in the second phase of the business plan competition of Sachsen-Anhalt